Publications

Welcome! Below, you’ll find a curated selection of our top publications. For a complete list of all available resources, click the button below to explore further.

• The LRRC family of BK channel regulatory subunits: potential roles in health and disease
  March 15, 2022
  The LRRC family of BK channel regulatory subunits: potential roles in health and diseaseGonzalez-Perez, V., Zhou, Y., Ciorba, M. A. & Lingle, C. J., Mar 15 2022, In: Journal of […]
• Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice
  January 19, 2021
  Goblet cell LRRC26 regulates BK channel activation and protects against colitis in miceGonzalez-Perez, V., Martinez-Espinosa, P. L., Sala-Rabanal, M., Bharadwaj, N., Xia, X. M., Chen, A. C., Alvarado, D., Gustafsson, […]
• Regulation of BK Channels by Beta and Gamma Subunits
  February 10, 2019
  Regulation of BK Channels by Beta and Gamma SubunitsGonzalez-Perez, V. & Lingle, C. J., Feb 10 2019, In: Annual review of physiology. 81, p. 113-137 25 p.Research output: Contribution to […]
• Regulatory γ1 subunits defy symmetry in functional modulation of BK channels
  October 2, 2018
  Regulatory γ1 subunits defy symmetry in functional modulation of BK channelsGonzalez-Perez, V., Johny, M. B., Xia, X. M. & Lingle, C. J., Oct 2 2018, In: Proceedings of the National […]
• Gating-induced large aqueous volumetric remodeling and aspartate tolerance in the voltage sensor domain of Shaker K⁺ channels
  August 7, 2018
  Gating-induced large aqueous volumetric remodeling and aspartate tolerance in the voltage sensor domain of Shaker K+ channelsDíaz-Franulic, I., González-Pérez, V., Moldenhauer, H., Navarro-Quezada, N. & Naranjo, D., Aug 7 2018, […]
• Knockout of the LRRC26 subunit reveals a primary role of LRRC26-containing BK channels in secretory epithelial cells
  May 2, 2017
  Knockout of the LRRC26 subunit reveals a primary role of LRRC26-containing BK channels in secretory epithelial cellsYang, C., Gonzalez-Perez, V., Mukaibo, T., Melvin, J. E., Xia, X. M. & Lingle, […]
• Knockout of Slo2.2 enhances itch, abolishes K_Na current, and increases action potential firing frequency in DRG neurons
  November 11, 2015
  Knockout of Slo2.2 enhances itch, abolishes KNa current, and increases action potential firing frequency in DRG neuronsMartinez-Espinosa, P. L., Wu, J., Yang, C., Gonzalez-Perez, V., Zhou, H., Liang, H., Xia, […]
• Two classes of regulatory subunits coassemble in the same BK channel and independently regulate gating
  September 21, 2015
  Two classes of regulatory subunits coassemble in the same BK channel and independently regulate gatingGonzalez-Perez, V., Xia, X. M. & Lingle, C. J., Sep 21 2015, In: Nature communications. 6, […]
• Functional regulation of BK potassium channels by γ1 auxiliary subunits
  April 1, 2014
  Functional regulation of BK potassium channels by γ1 auxiliary subunitsGonzalez-Perez, V., Xia, X. M. & Lingle, C. J., Apr 1 2014, In: Proceedings of the National Academy of Sciences of […]
• Knockout of the BK β2 subunit abolishes inactivation of BK currents in mouse adrenal chromaffin cells and results in slow-wave burst activity
  January 1, 2014
  Knockout of the BK β2 subunit abolishes inactivation of BK currents in mouse adrenal chromaffin cells and results in slow-wave burst activityMartinez-Espinosa, P. L., Yang, C., Gonzalez-Perez, V., Xia, X. […]
• Erratum: Stereospecific binding of a disordered peptide segment mediates BK channel inactivation (Nature (2012) 485 (133-136) DOI: 10.1038/nature10994)
  September 27, 2012
  Erratum: Stereospecific binding of a disordered peptide segment mediates BK channel inactivation (Nature (2012) 485 (133-136) DOI: 10.1038/nature10994)Gonzalez-Perez, V., Zeng, X. H., Henzler-Wildman, K. & Lingle, C. J., Sep 27 […]
• Stereospecific binding of a disordered peptide segment mediates BK channel inactivation
  May 3, 2012
  Stereospecific binding of a disordered peptide segment mediates BK channel inactivationGonzalez-Perez, V., Zeng, X. H., Henzler-Wildman, K. & Lingle, C. J., May 3 2012, In: Nature. 485, 7396, p. 133-136 […]
• Reduced voltage sensitivity in a K⁺-channel voltage sensor by electric field remodeling
  March 16, 2010
  Reduced voltage sensitivity in a K+-channel voltage sensor by electric field remodelingGonzález-Pérez, V., Stack, K., Boric, K. & Naranjo, D., Mar 16 2010, In: Proceedings of the National Academy of […]
• Slow inactivation in Shaker K channels is delayed by intracellular tetraethylammonium
  December 1, 2008
  Slow inactivation in Shaker K channels is delayed by intracellular tetraethylammoniumVivian, G. P., Neely, A., Tapia, C., Giovanni, G. G., Contreras, G., Orio, P., Lagos, V., Rojas, G., Estévez, T., […]
• Slow inactivation in voltage gated potassium channels is insensitive to the binding of pore occluding peptide toxins
  August 1, 2005
  Slow inactivation in voltage gated potassium channels is insensitive to the binding of pore occluding peptide toxinsOliva, C., González, V. & Naranjo, D., Aug 2005, In: Biophysical Journal. 89, 2, […]