Research in our lab studies the molecular and cellular mechanisms whereby ion channels and receptors mediate host defense, particularly in neurons, glial, and epithelial cells, in the contexts of homeostasis and inflammation. Specifically, we are currently focused on the impact of ion channels on intestinal epithelial (patho)physiology, and neuroinflammation.
Current projects:
- Role of LRRC26-associated BK channels in intestinal epithelial homeostasis and inflammation
- Role of potassium channels in opioid-induced hyperalgesia and chronic pain
Experimental Techniques
- Patch clamp electrophysiology
- Calcium imaging
- Live tissue imaging
- Molecular biology
- Biochemical assays
- Behavioral assays in rodents
- Tissue imaging and confocal microscopy
